Search results for "methods [Diffusion Tensor Imaging]"
showing 10 items of 992 documents
TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro
2017
International audience; The quest for chemicals able to operate at selected genomic loci in a spatiotemporally controlled manner is desirable to create manageable DNA damages. Mounting evidence now shows that alternative DNA structures, including G-quadruplexes and branched DNA (or DNA junctions), might hamper proper progression of replication fork, thus triggering DNA damages and genomic instability. Therefore, small molecules that stabilize these DNA structures are currently scrutinized as a promising way to create genomic defects that cannot be dealt with properly by cancer cells. While much emphasis has been recently given to G-quadruplexes and related ligands, we report herein on three…
An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo.
2021
Understanding brain operation demands linking basic behavioral traits to cell-type specific dynamics of different brain-wide subcircuits. This requires a system to classify the basic operational modes of neurons and circuits. Single-cell phenotyping of firing behavior during ongoing oscillations in vivo has provided a large body of evidence on entorhinal–hippocampal function, but data are dispersed and diverse. Here, we mined literature to search for information regarding the phase-timing dynamics of over 100 hippocampal/entorhinal neuron types defined in Hippocampome.org. We identified missing and unresolved pieces of knowledge (e.g., the preferred theta phase for a specific neuron type) a…
FRIPON: a worldwide network to track incoming meteoroids
2020
Context. Until recently, camera networks designed for monitoring fireballs worldwide were not fully automated, implying that in case of a meteorite fall, the recovery campaign was rarely immediate. This was an important limiting factor as the most fragile - hence precious - meteorites must be recovered rapidly to avoid their alteration. Aims. The Fireball Recovery and InterPlanetary Observation Network (FRIPON) scientific project was designed to overcome this limitation. This network comprises a fully automated camera and radio network deployed over a significant fraction of western Europe and a small fraction of Canada. As of today, it consists of 150 cameras and 25 European radio receiver…
Cruise passengers' expenditure at destinations: Review of survey techniques and data collection
2020
Spending by cruise passengers constitutes an important contribution to the economy of destinations. The issues related to the analysis of the expenditure have been widely debated for many years both in the scientific literature and in the common political debate. Despite 20 years of empirical research on this topic, not consolidated quantification methods exist to inform the debate. This work offers a brief review of the principal research on cruise tourist spending. It analyses the main characteristics of the surveys, reviews the different methods and techniques employed as well as assesses the main results. The article concludes with a discussion of the studies conducted and identifies fu…
GW170817: Implications for the Stochastic Gravitational-Wave Background from Compact Binary Coalescences
2018
The LIGO Scientific and Virgo Collaborations have announced the first detection of gravitational waves from the coalescence of two neutron stars. The merger rate of binary neutron stars estimated from this event suggests that distant, unresolvable binary neutron stars create a significant astrophysical stochastic gravitational-wave background. The binary neutron star background will add to the background from binary black holes, increasing the amplitude of the total astrophysical background relative to previous expectations. In the Advanced LIGO-Virgo frequency band most sensitive to stochastic backgrounds (near 25 Hz), we predict a total astrophysical background with amplitude $\Omega_{\rm…
Crystal structure of BaCa(CO3)2 alstonite carbonate and its phase stability upon compression
2021
Authors thank the financial support from the Spanish Ministerio de Ciencia, Innovación y Universidades (MICINN) and the Agencia Estatal de Investigación under projects MALTA Consolider Ingenio 2010 network (MAT2015-71070- REDC) and PGC2018-097520-A-I00 (cofinanced by EU FEDER funds) and from the Generalitat Valenciana under project PROMETEO/2018/123. D.S.-P. and A.O.R. acknowledge the financial support of the Spanish MINECO for RyC-2014-15643 and RyC-2016-20301 Ramón y Cajal grants, respectively. C.P. acknowledges the financial support from the Spanish Ministerio de Economia y Competitividad (MINECO project FIS2017-83295-P). Authors also thank Dr. Nicolescu and the Mineralogy and Meteoritic…
Focal shift in optical waves with off-axis focus
2003
We present a formulation for a suitable description of the focal shift in optical waves that have an off-axis focus. This shift that is primarily produced along the chief axis is given in terms of the focal distance and depends only on a parameter that is named as the generalized Fresnel number. Any non-uniform, either truncated and non-apertured optical beam with off-axis focus may be considered.
Single-zone-plate achromatic fresnel-transform setup: Pattern tunability
1997
Abstract White-light point-source illumination results in the chromatic blurring of the optical field diffracted by an aperture. In this paper, broadband dispersion compensation for a continuous set of Fresnel diffraction patterns associated with an arbitrary input transparency is carried out, in a sequential way, by means of a single on-axis blazed zone plate. The input is illuminated with a white-light converging spherical wavefront and the diffractive lens is inserted at the virtual source plane. We recognize that the position of the input along the optical axis permits to achieve a different achromatic Fresnel diffraction pattern with low residual chromatic aberrations. The theory deriv…
Totally incoherent optical processing operations with achromatic diffraction-based setups
2000
We report on a novel family of totally incoherent, chromatic-dispersion compensated hybrid (refractive-diffractive) lens setups for implementing, in the Fraunhofer or in the Fresnel diffraction region, different achromatic diffraction-based processing operations.
Three-dimensional behavior of apodized nontelecentric focusing systems.
2002
The scalar field in the focal volume of nontelecentric apodized focusing systems cannot be accurately described by the Debye integral representation. By use of the Fresnel–Kirchhoff diffraction formula it is found that, if the aperture stop is axially displaced, the focal-volume structure is tuned. We analyze the influence of the apodizing function and find that, whereas axially superresolving pupil filters are highly sensitive to the focal-volume reshaping effect, axially apodizing filters are more inclined to the focal-shift effect.